Improvements In AF Ablation Outcome Will Be Based More On Technological Advancement Versus Mechanistic Understanding.
نویسندگان
چکیده
Atrial fibrillation (AF) is one of the most common cardiac arrhythmias. Catheter ablation has proven more effective than antiarrhythmic drugs in preventing clinical recurrence of AF, however long-term outcome remains unsatisfactory. Ablation strategies have evolved based on progress in mechanistic understanding, and technologies have advanced continuously. This article reviews current mechanistic concepts and technological advancements in AF treatment, and summarizes their impact on improvement of AF ablation outcome.
منابع مشابه
Focal Impulse And Rotor Mapping (FIRM): Conceptualizing And Treating Atrial Fibrillation.
Current approaches for the ablation of atrial fibrillation are often effective, but only partially rooted in mechanistic understanding. Accordingly, they are unable to predict whether a given patient will or will not do well, or which lesions sets should or should not be performed - in any given patient. This goal would require clearer mechanistic definition of what sustains AF after it has bee...
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OBJECTIVES We hypothesized that human atrial fibrillation (AF) may be sustained by localized sources (electrical rotors and focal impulses), whose elimination (focal impulse and rotor modulation [FIRM]) may improve outcome from AF ablation. BACKGROUND Catheter ablation for AF is a promising therapy, whose success is limited in part by uncertainty in the mechanisms that sustain AF. We develope...
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Atrial fibrillation (AF) is one of the most common arrhythmias encountered in clinical practice today. Over the last 20 years, the frequency of use of catheter ablation to treat AF has grown, commensurate with the rise in arrhythmia burden and via a number of technical advancements. These developments can be divided into new techniques for myocardial ablation, improvements in the understanding ...
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ورودعنوان ژورنال:
- Journal of atrial fibrillation
دوره 7 2 شماره
صفحات -
تاریخ انتشار 2014